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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIRT2
All Species:
23.03
Human Site:
S311
Identified Species:
42.22
UniProt:
Q8IXJ6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXJ6
NP_036369.2
389
43182
S311
G
G
G
M
D
F
D
S
K
K
A
Y
R
D
V
Chimpanzee
Pan troglodytes
XP_001168156
319
35635
E263
Q
G
C
L
A
L
A
E
L
L
G
W
K
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855382
347
38546
L291
C
L
A
L
A
D
L
L
G
W
K
K
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDQ8
389
43238
S311
G
G
G
M
D
F
D
S
K
K
A
Y
R
D
V
Rat
Rattus norvegicus
Q5RJQ4
350
39301
L294
C
D
Q
G
C
L
A
L
A
D
L
L
G
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001017414
412
44719
S324
G
C
G
M
D
F
D
S
D
K
A
Y
R
D
V
Frog
Xenopus laevis
NP_001088636
413
45548
S338
G
G
G
M
D
F
D
S
E
K
A
Y
R
D
V
Zebra Danio
Brachydanio rerio
Q7ZVK3
379
42296
S308
G
G
G
M
D
F
D
S
D
K
A
Y
R
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650880
355
40094
L299
C
D
A
G
V
M
A
L
A
K
A
L
G
W
D
Honey Bee
Apis mellifera
XP_393038
355
40940
L299
T
Q
D
R
L
S
R
L
L
G
L
R
H
G
L
Nematode Worm
Caenorhab. elegans
Q21921
607
68747
K479
R
N
S
D
D
I
L
K
K
I
K
H
P
R
L
Sea Urchin
Strong. purpuratus
XP_001195952
400
43895
S307
P
S
G
M
D
F
D
S
D
D
K
Y
R
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53686
357
39961
S301
Q
G
G
M
G
D
N
S
K
E
Q
L
L
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82
N.A.
75.8
N.A.
87.6
78.4
N.A.
N.A.
63.3
63.4
63.5
N.A.
43.7
47.5
25.2
47.2
Protein Similarity:
100
82
N.A.
82.2
N.A.
94.5
84.5
N.A.
N.A.
78.4
76
77.8
N.A.
59.6
61.4
39.8
64.7
P-Site Identity:
100
6.6
N.A.
0
N.A.
100
0
N.A.
N.A.
86.6
93.3
93.3
N.A.
13.3
0
13.3
66.6
P-Site Similarity:
100
26.6
N.A.
6.6
N.A.
100
0
N.A.
N.A.
86.6
100
93.3
N.A.
13.3
6.6
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
16
0
24
0
16
0
47
0
0
0
0
% A
% Cys:
24
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
8
8
54
16
47
0
24
16
0
0
0
47
8
% D
% Glu:
0
0
0
0
0
0
0
8
8
8
0
0
8
8
16
% E
% Phe:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% F
% Gly:
39
47
54
16
8
0
0
0
8
8
8
0
16
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
31
47
24
8
8
8
8
% K
% Leu:
0
8
0
16
8
16
16
31
16
8
16
24
8
8
16
% L
% Met:
0
0
0
54
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
16
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
8
0
0
0
0
8
47
8
0
% R
% Ser:
0
8
8
0
0
8
0
54
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
8
0
16
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _